Faster diagnosis. Improved treatments. Revolutionary research. Breakthroughs in care and knowledge at the CHOP Center for Pediatric Inflammatory Bowel Disease (IBD) are creating new hope for children with this painful disease. But we can’t do it alone.
Did You Know?
Inflammatory bowel disease is the fastest-growing autoimmune disorder in children younger than 5. The Center for Pediatric Inflammatory Bowel Disease at CHOP annually treats more than 1,800 young patients who suffer from abdominal pain, intestinal inflammation and other symptoms.
The past few years have produced an explosion of knowledge about the genetics of IBD and expanded treatment options. Our expert gastroenterologists, geneticists, and researchers are actively working together to evaluate DNA and microbiome with the goal of developing the next innovative treatments for individuals with IBD.
Creation of an IBD biorepository
CHOP is creating a repository of biological samples – blood, urine and stool — from patient colonoscopies and surgical resections for IBD and gastrointestinal (GI) research.
Increasing diversity of IBD research patients
In collaboration with Emory University, CHOP is completing a “Genesis AA” study to compare patients – African American vs. Caucasians of European descent – who have IBD. The goal is to identify any genetic similarities in how the disease occurs (inherited vs. acquired) in each population, as well improve the chances of gene discoveries to better support African American patients.
Growing “good” gut bacteria
In the “Treating IBD with Inulin” study, children aged 8-12 with IBD in clinical remission and who are not taking medication, are given a food supplement called inulin to potentially improve their overall health. The hope is by growing healthy bacteria in their gut, it will decrease inflammation.
Will medication improve IBD symptoms?
CHOP is collaborating with MassGeneral Hospital for Children in Massachusetts to study whether biomarkers in a patients’ blood can offer early clues about whether Remicade (infliximab) could be an effective treatment for certain individuals with IBD.
Want a closer look at what your dollars are funding?
Follow CHOP researchers Melissa and Corey as they share a behind-the-scenes look at their work on the Biorepository Study – one of many research projects funded by Walk for Hope!
Patient Ambassadors for Walk for Hope have a big job to do. It’s up to them to represent the millions of children living with inflammatory bowel disease. As they share their stories, they help the world understand the toll that IBD takes and why it’s worth supporting institutions like Children’s Hospital of Philadelphia.